GTP 14564
¥0
- 货号
- GTP 14564
- CAS 号
- [34823-86-4]
- 分子式
- C 15 H 10 N 2 O
- 分子量
- 234.26
- 规格
- 10mg
- 规格(数值)
- 10 mg
- 别名
- 3-Phenyl-1H-benzofuro[3,2-c]pyrazol e
- 溶解性
- Soluble to 100 mM in DMSO and to 25 mM in ethanol
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Potent, selective inhibitor of class III receptor tyrosine kinases (IC 50 values are 0.3 μM for c-Fms, c-Kit, FLT3 and ITD-FLT3 and 1 μM for PDGFRβ). Displays no selectivity for ERK1, ERK2, EGFR, MEK1, HER2, Src, Abl, PKC, PKA and Akt (IC50 > 10 μM). Inhibits FL-dependent proliferation in BaF/ITD-FLT3 cells more potently than BaF/wt-FLT3 cells; anti-leukaemic. Purity: >99 %