GSK 429286
¥0
- 货号
- GSK 429286
- 分子式
- C 21 H 16 F 4 N 4 O 2
- 分子量
- 432.37
- 规格
- 1mg; 50mg
- 规格(数值)
- 1 mg
- 别名
- 4-[4-(Trifluoromethyl)phenyl]-N-(6- Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-1,4,5,6-tet rahydro-3-pyridinecarboxamide
- 溶解性
- Soluble to 100 mM in DMSO and to 25 mM in ethanol
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Selective Rho-kinase inhibitor (IC 50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively). Reverses adrenalin-induced contraction of the rat aortic ring (IC 50 = 190 nM) and causes a dose-dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats. Orally active. Purity: >97 %