PSB 11 hydrochloride
¥0
- 货号
- PSB 11 hydrochloride
- CAS 号
- [444717-56-0]
- 分子式
- C 16 H 17 N 5 O.HCl
- 分子量
- 331.8
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- (8R)-8-Ethyl-1,4,7,8-tetrahydro-4-5 H-imidazo[2,1-i]purin-5-one hydrochloride
- 溶解性
- Soluble to 20 mM in DMSO
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Potent and selective antagonist for the human adenosine A 3 receptor, with low affinity for the rat A 3 receptor (K i values are 2.3 and > 10000 nM respectively). Displays > 1000-fold selectivity over human A 1 and A 2A receptors (K i values are 4.1 and 3.3 μM respectively) and > 180-fold selectivity over rat A 1 , rat A 2A and mouse A 2B receptors. Acts as an inverse agonist in the [35S]GTPγS binding assay in hA 3 -CHO cells (IC 50 = 36 nM). Purity: >98 %