XR 9051 HCl
¥0
- 货号
- XR 9051 HCl
- CAS 号
- [180422-22-4]
- 分子式
- C 39 H 36 N 4 O 5 .HCl
- 分子量
- 679.2
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- N-[4-[2-(3,4-Dihydro-6,7-dimethoxy- 2(1H)-isoquinolinyl)ethyl]phenyl]-3-[(Z)-[(5Z)-4-m ethyl-3,6-dioxo-5-(phenylmethylene)piperazinyliden e]methyl]benzamide hydrochloride
- 溶解性
- Soluble to 100 mM in DMSO
- 储存条件
- Store at -20°C
- 销量
- 0
产品描述
Potent modulator of P-glycoprotein-mediated multidrug resistance (MDR) that inhibits the binding of cytotoxics to P-glycoprotein (EC 50 = 134 nM). Reverses resistance to a variety of cytotoxic drugs (including doxorubicin, etoposide and vincristine) in several murine and human P-gp-overexpressing cell lines. Orally active. Purity: >98 %