XE 991 dihydrochloride
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- 货号
- XE 991 dihydrochloride
- CAS 号
- [122955-42-4]
- 分子式
- C 26 H 20 N 2 O.2HCl
- 分子量
- 449.37
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- 10,10-bis(4-Pyridinylmethyl)-9(10H) -anthracenone dihydrochloride
- 溶解性
- Soluble to 100 mM in water
- 储存条件
- Desiccate at RT
- 销量
- 0
产品描述
Potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks KCNQ2+3/M-currents (IC 50 = 0.6 - 0.98 μM) and KCNQ1 homomeric channels (IC 50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC 50 = 11.1 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo. Purity: >99 %