YM 90709
¥0
- 货号
- YM 90709
- CAS 号
- [163769-88-8]
- 分子式
- C 22 H 21 N 3 O 2
- 分子量
- 359.43
- 规格
- 10mg
- 规格(数值)
- 10 mg
- 别名
- 5,6-Dihydro-2,3-dimethoxy-6,6-dimet hylbenz[7,8]indolizino[2,3-b]quinoxaline
- 溶解性
- Soluble to 25 mM in ethanol and to 50 mM in DMSO
- 储存条件
- Store at RT
- 销量
- 0
产品描述
Novel, selective inhibitor of interleukin-5 (IL-5) (IC 50 = 0.45 - 1 mM). Inhibits IL-5-prolonged eosinophil survival and IL-5-induced tyrosine phosphorylation of JAK2 without inhibiting GM-CSF-mediated effects. Inhibits antigen-induced eosinophil and lymphocyte recruitment in rat airways in vivo, without affecting peripheral blood or bone marrow leukocytes. Purity: >99 %