YM 58483
¥0
- 货号
- YM 58483
- CAS 号
- [223499-30-7]
- 分子式
- C 15 H 9 F 6 N 5 OS
- 分子量
- 421.32
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- N-[4-[3,5-Bis(trifluoromethyl)-1H-p yrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-c arboxamide
- 溶解性
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin-induced sustained Ca2+ influx (IC 50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T-cells in vitro. Purity: >99 %