YM 511
¥0
- 货号
- YM 511
- CAS 号
- [148869-05-0]
- 分子式
- C 16 H 12 BrN 5
- 分子量
- 354.2
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- 4-[[(4-Bromophenyl)methyl]-4H-1,2,4 -triazol-4-ylamino]benzonitrile
- 溶解性
- Soluble to 100 mM in DMSO and to 25 mM in ethanol
- 储存条件
- Store at RT
- 销量
- 0
产品描述
Orally active, potent aromatase (CYP19) inhibitor (IC 50 values are 0.4 and 0.12 nM at rat ovary and human placenta cells respectively) that only weakly inhibits the synthesis of other steroid hormones. Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro (IC 50 = 0.13 nM). Purity: >99 %