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YM 26734

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货号
YM 26734
CAS 号
[144337-18-8]
分子式
C 45 H 62 O 8
分子量
730.97
规格
10mg
规格(数值)
10 mg
别名
1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4- hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydr oxy-1,3-phenylene]bis-1-dodecanone
溶解性
Soluble to 100 mM in DMSO and to 100 mM in ethanol
储存条件
Store at -20°C
销量
0

产品描述

Competitive inhibitor of secretory phospholipase A 2 (sPLA 2 ) that exhibits a broad inhibitory profile to several sPLA 2 s (IC 50 values are 0.2, 1, 1, 1 and 3 μM for sPLA 2 -X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA 2 -IIF and no activity at cytosolic PLA 2 , cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema. Purity: >96 %

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