YM 202074
¥0
- 货号
- YM 202074
- CAS 号
- [299900-84-8]
- 分子式
- C 22 H 30 N 4 O 2 S.1.5C 4 H 4 O 4
- 分子量
- 588.67
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- N-Cyclohexyl-6-[[N-(2-methoxyethyl) -N-methylamino]methyl]-N-methylthiazolo[3,2-a]benz oimidazole-2-carboxamide sesquifumarate
- 溶解性
- Soluble to 20 mM in water and to 100 mM in DMSO
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
High affinity, selective metabotropic glutamate receptor type 1 (mGlu 1 ) antagonist. Binds an allosteric site of the rat mGlu 1 receptor with a K i of 4.8 nM. Inhibits mGlu 1 -mediated inositol phosphates production (IC 50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo. Purity: >99 %