Y-27632 dihydrochloride
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- 货号
- Y-27632 dihydrochloride
- CAS 号
- [146986-50-7]
- 分子式
- C 14 H 21 N 3 O.2HCl
- 分子量
- 320.26
- 规格
- 1mg; 50mg
- 规格(数值)
- 1 mg
- 别名
- trans-4-[(1R)-1-Aminoethyl]-N-4-pyr idinylcyclohexanecarboxamide dihydrochloride
- 溶解性
- Soluble to 100 mM in water
- 储存条件
- Desiccate at RT
- 销量
- 0
产品描述
Selective inhibitor of the Rho-associated protein kinase p160ROCK. K i values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, cAMP-dependent protein kinase and myosin light-chain kinase respectively. Also inhibits the protein kinase C-related protein kinase, PRK2 (IC 50 = 600nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells undergoing cryopreservation. Purity: >98 %