Y 134
¥0
- 货号
- Y 134
- CAS 号
- [849662-80-2]
- 分子式
- C 28 H 28 N 2 O 3 S
- 分子量
- 472.6
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- [6-Hydroxy-2-(4-hydroxyphenyl)benzo [b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl ]phenyl]methanone
- 溶解性
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- 储存条件
- Desiccate at RT
- 销量
- 0
产品描述
Selective estrogen receptor modulator (SERM) that displays selectivity for ERα over ERβ (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells. Purity: >98 %