Zoniporide dihydrochloride
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- 货号
- Zoniporide dihydrochloride
- CAS 号
- [241800-97-5]
- 分子式
- C 17 H 16 N 6 O.2HCl
- 分子量
- 393.27
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- [1-(Quinolin-5-yl)-5-cyclopropyl-1H -pyrazole-4-carbonyl]guanidine dihydrochloride
- 溶解性
- Soluble to 100 mM in water and to 100 mM in DMSO
- 储存条件
- Desiccate at -20°C
- 销量
- 0
产品描述
Sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor that displays selectivity over other NHE isoforms (K i values are 14, 2200 and 220000 nM for human NHE-1, human NHE-2 and rat NHE-3 respectively). Inhibits NHE-1 dependent 22Na+ uptake in vitro (IC 50 = 14 nM) and provides cardioprotection from myocardial ischemic injury in vivo (EC 50 = 0.25 nM). Purity: >99 %