ZM 447439
¥0
- 货号
- ZM 447439
- CAS 号
- [331771-20-1]
- 分子式
- C 29 H 31 N 5 O 4
- 分子量
- 513.59
- 规格
- 10mg
- 规格(数值)
- 10 mg
- 别名
- N-[4-[[6-Methoxy-7-[3-(4-morpholiny l)propoxy]-4-quinazolinyl]amino]phenyl]benzamide
- 溶解性
- Soluble to 100 mM in DMSO
- 储存条件
- Desiccate at RT
- 销量
- 0
产品描述
Novel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC 50 values are 50, 250 and 1000 nM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC 50 > 10 μM). Inhibits cell division and displays selective toxicity towards proliferating tumor cells versus non-dividing cells. Purity: >99 %