ZM 336372
¥0
- 货号
- ZM 336372
- CAS 号
- [208260-29-1]
- 分子式
- C 23 H 23 N 3 O 3
- 分子量
- 389.45
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- 3-(Dimethylamino)-N-[3-[(4-hydroxyb enzoyl)-amino]-4-methylphenyl]benzamide
- 溶解性
- Soluble to 100 mM in DMSO
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Potent, selective inhibitor of c-Raf in vitro (IC 50 = 70 nM for inhibition of human c-Raf). Shows 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC 50 = 2 μM). Selective over 17 other protein kinases including PKA, PKC, p42 MAPK, CDK1 and SAPK1/JNK (up to 50 μM). Also available as part of the MAPK Cascade Inhibitor Tocriset™. Purity: >98 %