ZM 323881 hydrochloride
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- 货号
- ZM 323881 hydrochloride
- CAS 号
- [324077-30-7]
- 分子式
- C 22 H 18 FN 3 O 2 .HCl
- 分子量
- 411.86
- 规格
- 1mg; 10mg
- 规格(数值)
- 1 mg
- 别名
- 5-((7-Benzyloxyquinazolin-4-yl)amin o)-4-fluoro-2-methylphenol hydrochloride
- 溶解性
- Soluble to 50 mM in DMSO
- 储存条件
- Desiccate at +4°C
- 销量
- 0
产品描述
Potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. Selectively inhibits VEGFR-2 (IC 50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC 50 > 50 μM). Inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC 50 = 8 nM). Purity: >99 %