ZK 200775
¥0
- 货号
- ZK 200775
- CAS 号
- [161605-73-8]
- 分子式
- C 14 H 15 N 3 O 6 F 3 P
- 分子量
- 409.25
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- [[3,4-Dihydro-7-(4-morpholinyl)-2,3 -dioxo-6-(trifluoromethyl)-1(2H)-quinoxalinyl]meth yl]phosphonic acid
- 溶解性
- Soluble to 100 mM in DMSO and to 50 mM in ethanol
- 储存条件
- Desiccate at +4°C
- 销量
- 0
产品描述
Competitive AMPA/kainate antagonist. In rat cortical membranes, displays high affinity for [3H]-AMPA (K i = 120 nM) and [3H]-CNQX (K i = 32 nM) binding sites and low affinity for kainate and NMDA channel-associated binding sites (IC 50 values range from 2.5 to 11 μM). Inhibits currents induced by AMPA, kainate and NMDA with IC 50 values of 21 nM, 27 nM, and > 1 μM respectively. Displays anxiolytic, anticonvulsant and muscle relaxant activity in vivo. Purity: >99 %