ZIP
¥0
- 货号
- ZIP
- CAS 号
- [863987-12-6]
- 分子式
- C 90 H 154 N 30 O 17
- 分子量
- 1928.4
- 规格
- 1mg
- 规格(数值)
- 1 mg
- 储存条件
- Desiccate at -20°C
- 销量
- 0
产品描述
Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC 50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.