Zileuton
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- 货号
- Zileuton
- CAS 号
- [111406-87-2]
- 分子式
- C 11 H 12 N 2 O 2 S
- 分子量
- 236.29
- 规格
- 10mg; 50mg
- 规格(数值)
- 10 mg
- 别名
- N-(1-Benzo[b]thien-2-ylethyl)-N-hyd roxyurea
- 溶解性
- Soluble to 100 mM in DMSO
- 储存条件
- Store at +4°C
- 销量
- 0
产品描述
Orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB 4 synthesis (IC 50 values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively). Inhibits antigen-induced contraction of tracheal strips in vitro (IC 50 = 6 μM) and exhibits antiasthmatic activity in vivo. Also weakly inhibits CYP1A2 (K i = 66 - 98 μM). Purity: >99 %