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Wortmannin
¥0
- 货号
- HW5769
- CAS 号
- [19545-26-7]
- 分子式
- C23H24O8
- 分子量
- 428.43
- 规格
- 1mg; 5mg
- 规格(数值)
- 1 mg
- 别名
- Wartmannin
- 溶解性
- Soluble in methanol and DMSO
- 应用说明
- 97%
- 熔点
- 240°C
- 储存条件
- -20°C
- 销量
- 0
产品描述
Boulton S, Kyle S, Yalcintepe L, Durkacz BW. Carcinogenesis. 17 : 2285 -90 (1996). Ng SSW, Tsao MS, Chow S, Hedley DW. Cancer Res. 60: 5451-5 (2000). Kubota N, Okada S, Inada T, Ohnishi K, Ohnishi T. Cancer Lett. 161:141-7 (2000). Wortmannin is an inhibitor of PI3-K and DNa-dependent protein kinase, which is known to mediate DNA double strand break repair. It induces apoptosis and also sensitize cells to ionizing radiation.