HA4443 蒜氨酸,L(+)Alliin 556-27-4
- 货号
- HA4443
- CAS 号
- 556-27-4
- 分子式
- C6H11NO3S
- 分子量
- 177.22
- 规格
- 25mg; 100mg
- 规格(数值)
- 25 mg
- 别名
- 3-(2-Propenylsulfinyl) alanine 3-[(S)-2-Propenylsulfinyl]-L-alanine S-Allyl-L-cysteine sulfoxide 3-(Allylsulfinyl)alanin Alliin EINECS 209-118-9 S-Allyl-L-cystein-S-oxid
- 溶解性
- Soluble in water. Insoluble in ethanol, or acetone
- 应用说明
- ≥98%
- 熔点
- 164-166°C
- 储存条件
- -20℃
- 销量
- 0
产品描述
L-(+)-Alliin is a cysteine derivative isolated from Allium; it exhibits anti-inflammatory, neuromodulatory, anti-diabetic, anti-hyperlipidemic, antioxidative, cardioprotective, and anti-angiogenic activities; it is the optically active and orally bioavailable isomer of alliin. In adipocytes, L-alliin inhibits LPS-stimulated activation of ERK1/2 and increases in inflammatory signaling. In animal models of myocardial infarction, L-alliin increases activity of superoxide dismutase, glutathione peroxidase, catalase, and glutathione-S-transferase. L-Alliin also activates NMDA-R subunits NR2A and NR2B. In diabetic rats, this compound decreases levels of LDL, VLDL, glucose, triglycerides, total cholesterol, and total lipids. Additionally, L-alliin inhibits VEGF-induced angiogenesis and FGF2 and VEGF secretion in fibrosarcoma cells.