H19556 C18 Ceramide (d18:1/18:0) 2304-81-6

产品描述

C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice. Increased expression of C18 ceramide reduces cell growth in UM-SCC-22A squamous cell carcinoma cells. It is selectively downregulated in 32 human head and neck squamous cell carcinoma tumor tissues as compared to non-squamous tumor tissues. C18 Ceramide concentration is significantly higher in muscle tissue of type 2 diabetic patients compared with non-diabetic patients and is positively correlated to body mass index and inversely related to insulin sensitivity.[Matreya, LLC. Catalog No. 1832] C18神经酰胺是一种内源性生物活性鞘脂。 它是在大脑组织中发现的主要短链神经酰胺，其合成受小鼠长寿保证同源物1（Lass1）的调节。C18神经酰胺表达的增加降低了UM-SCC-22A鳞状细胞癌细胞的细胞生长。与非鳞状肿瘤组织相比，在32种人的头颈部鳞状细胞癌肿瘤组织中选择性地下调了α1α-β-内化。 与非糖尿病患者相比，2型糖尿病患者肌肉组织中的C18神经酰胺浓度显着更高，并且与体重指数呈正相关，与胰岛素敏感性呈负相关。3[ Matreya，LLC。 货号1832] 神经酰胺是由神经鞘氨醇长链碱基与脂肪酸组成神经鞘氨脂质一种。神经酰胺(Ceramide)是以神经酰胺为骨架的一类磷脂，主要有神经酰胺磷酸胆碱和神经酰胺磷酸乙醇胺，磷脂是细胞膜的主要成分，神经酰胺（Ceramides, Cers）存在于所有的真核细胞中，对细胞分化、增殖、凋亡、衰老等生命活动具有重要调节作用。 上海惠诚生物优势提供神经酰胺系列产品,咨询订购热线：021-60498804 C2 Ceramide (d18:1/2:0) C6 Ceramide (d18:1/6:0) C8 Ceramide (d18:1/8:0) C16 Ceramide (d18:1/16:0) C16 Ceramide (d18:1(14Z)/16:0) C18 Ceramide (d18:1/18:0) C22 Ceramide (d18:1(14Z)/22:0) C22:1 Ceramide (d18:1(14Z)/22:1(13Z)) C24 Ceramide (d18:1/24:0) C24 Ceramide (d18:1(14Z)/24:0) C6 Ceramide-d7 (d18:1-d7/6:0) C16 Ceramide-d7 (d18:1-d7/16:0) C18 Ceramide-d7 (d18:1-d7/18:0) C24 Ceramide-d7 (d18:1-d7/24:0) C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))