H62540 C8 Ceramide (d18:1/8:0) 74713-59-0
- 货号
- H62540
- CAS 号
- 74713-59-0
- 分子式
- C26H51NO3
- 分子量
- 425.7
- 规格
- 10mg; 25mg
- 规格(数值)
- 10 mg
- 别名
- N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide;C8;Ceramide Ceramide (d18:1/8:0);Cer(d18:1/8:0);N-octanoyl-D-erythro-Sphingosine N-Octanoylsphingosine
- 外观
- A crystalline solid
- 溶解性
- acidic PBS: 20 mg/ml;Ethanol: >33 mg/ml;PBS pH 7.2:
- 应用说明
- ≥98%
- 稳定性
- ≥ 1 year
- 规格分类
- Glycerols, Fatty Acid Derivatives & Lipids; Inhibitors; Activators; Protein Kinase Inhibitors and Activators
- 储存条件
- -20°C
- 销量
- 0
产品描述
C8 Ceramide (d18:1/8:0) is a cell- permeable analog of naturally occurring ceramides. Unlike C2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels. 1 For this reason, treatment of cells with C8 ceramide (d18:1/8:0) may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C8 Ceramide (d18:1/8:0) likely mediates many diverse biological activities, as do natural ceramides. It promotes the differentiation of human keratinocytes 2 and induces apoptosis of both human leukemia cells and the U937 cell line. 1 , 3 神经酰胺是由神经鞘氨醇长链碱基与脂肪酸组成神经鞘氨脂质一种。神经酰胺(Ceramide)是以神经酰胺为骨架的一类磷脂，主要有神经酰胺磷酸胆碱和神经酰胺磷酸乙醇胺，磷脂是细胞膜的主要成分，神经酰胺（Ceramides, Cers）存在于所有的真核细胞中，对细胞分化、增殖、凋亡、衰老等生命活动具有重要调节作用。 上海惠诚生物优势提供神经酰胺系列产品,咨询订购热线：021-60498804 C2 Ceramide (d18:1/2:0) C6 Ceramide (d18:1/6:0) C8 Ceramide (d18:1/8:0) C16 Ceramide (d18:1/16:0) C16 Ceramide (d18:1(14Z)/16:0) C18 Ceramide (d18:1/18:0) C22 Ceramide (d18:1(14Z)/22:0) C22:1 Ceramide (d18:1(14Z)/22:1(13Z)) C24 Ceramide (d18:1/24:0) C24 Ceramide (d18:1(14Z)/24:0) C6 Ceramide-d7 (d18:1-d7/6:0) C16 Ceramide-d7 (d18:1-d7/16:0) C18 Ceramide-d7 (d18:1-d7/18:0) C24 Ceramide-d7 (d18:1-d7/24:0) C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))