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H62525 C6 Ceramide (d18:1/6:0) 124753-97-5

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货号
H62525
CAS 号
124753-97-5
分子式
C24H47NO3
分子量
397.6
规格
5mg; 10mg
规格(数值)
5 mg
别名
N-Caproyl-C18-sphingosine;Cer(18:1/6:0);Ceramide (d18:1/6:0) ;C6 Ceramide N-hexanoyl-D-erythro-sphingosine
外观
Off-White Solid
溶解性
DMF: >22 mg/ml DMSO: >20 mg/ml
应用说明
≥98%
熔点
69-72°C
稳定性
≥ 1 year
规格分类
Fatty Acid Derivatives & Lipids; Glycerols, Inhibitors, Isotope Labelled Compounds, Protein Kinase Inhibitors and Activators
储存条件
-20°C Freezer
销量
0

产品描述

C6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides. 1 C6 ceramide mediates many diverse biological activities including apoptosis, 2 activation of protein phosphatase 2A, 1 , 3 and inhibition of the mitochondrial respiratory chain. 4 It also enhances the expression of COX-2 in rat granulosa cells 5 and stimulates the growth of bovine aortic smooth muscle cells. 6 C6 ceramide acts in neuronal axons to inhibit neurite growth. 7 神经酰胺是由神经鞘氨醇长链碱基与脂肪酸组成神经鞘氨脂质一种。神经酰胺(Ceramide)是以神经酰胺为骨架的一类磷脂,主要有神经酰胺磷酸胆碱和神经酰胺磷酸乙醇胺,磷脂是细胞膜的主要成分,神经酰胺(Ceramides, Cers)存在于所有的真核细胞中,对细胞分化、增殖、凋亡、衰老等生命活动具有重要调节作用。 上海惠诚生物优势提供神经酰胺系列产品,咨询订购热线:021-60498804 C2 Ceramide (d18:1/2:0) C6 Ceramide (d18:1/6:0) C8 Ceramide (d18:1/8:0) C16 Ceramide (d18:1/16:0) C16 Ceramide (d18:1(14Z)/16:0) C18 Ceramide (d18:1/18:0) C22 Ceramide (d18:1(14Z)/22:0) C22:1 Ceramide (d18:1(14Z)/22:1(13Z)) C24 Ceramide (d18:1/24:0) C24 Ceramide (d18:1(14Z)/24:0) C6 Ceramide-d7 (d18:1-d7/6:0) C16 Ceramide-d7 (d18:1-d7/16:0) C18 Ceramide-d7 (d18:1-d7/18:0) C24 Ceramide-d7 (d18:1-d7/24:0) C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))

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